Project number
23028
Organization
Roche Tissue Diagnostics
Academic year
2022-2023
Roche’s BenchMark ULTRA staining instrument has a variety of internal conditions, and it controls multiple chemical and physical parameters of the tissue staining process. The residual fluid volume on a microscope slide must be known and controlled. Currently, a technician measures the volume using a Kimwipe and an analytical balance. The team designed an optical approach to measure the volume of residual fluid on the microscope slide with less user interaction than the existing method.
The new system captures side-view images of fluid on a microscope slide and processes the images, measuring the height of the fluid at different points. A Raspberry Pi microcontroller directs the image processing, and a machine learning algorithm is trained to estimate and display the fluid volume onto an LCD screen.
The team designed and manufactured a plastic housing for the camera module that integrates directly onto the slide drawer of the staining instrument. They also manufactured an external housing for the Raspberry Pi and its associated components. Designed for simplicity, this system will greatly reduce the amount of time spent measuring residual fluid volumes.
The new system captures side-view images of fluid on a microscope slide and processes the images, measuring the height of the fluid at different points. A Raspberry Pi microcontroller directs the image processing, and a machine learning algorithm is trained to estimate and display the fluid volume onto an LCD screen.
The team designed and manufactured a plastic housing for the camera module that integrates directly onto the slide drawer of the staining instrument. They also manufactured an external housing for the Raspberry Pi and its associated components. Designed for simplicity, this system will greatly reduce the amount of time spent measuring residual fluid volumes.